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To lower the chance of getting cut, bruised or injured, use caution with sharp objects like safety razors or...Nervous system symptoms generally began the first or second day of therapy and often resolved after 2 to 4 weeks. Nervous system symptoms of any grade and regardless of causality (52.7%) included dizziness, insomnia, impaired concentration, somnolence, abnormal dreams, hallucinations, amnesia, agitation, euphoria, depersonalization, confusion, abnormal thinking, and stupor during clinical trials with this drug in combination with other antiretroviral agents. These symptoms were mild in 33.3%, moderate in 17.4%, and severe in 2% of patients. Therapy was discontinued in 2.1% of patients due to these side effects.

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Patients using MAOIs may experience drowsiness and dizziness; insomnia is also possible. Other side effects of MAOIs include weight gain, sexual dysfunction, constipation, and other gastrointestinal problems.

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5. Gatanaga H, Hayashida T, Tsuchiya K, et al. "Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6 *6 and *26." Clin Infect Dis 45 (2007): 1230-7

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