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Cyclosporine (Neoral, Sandimmune) HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist. Learn all preparation and usage instructions from your health care professional and the product package. Before using, check this product visually for particles or discoloration. If either is present, do not use the insulin. Insulin regular should be clear and colorless. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin and to avoid developing problems under the skin (lipodystrophy). Insulin regular may be injected in the stomach area, the thigh, the buttocks, or the back of the upper arm. Do not inject into a vein or muscle because very low blood sugar (hypoglycemia) may occur. Do not rub the area after the injection. Do not inject into skin that is red, swollen, or itchy. Do not inject cold insulin because this can be painful. The insulin container you are currently using can be kept at room temperature (see also Storage section). Inject this medication under the skin as directed by your doctor, usually 30 minutes before meals. Because this insulin is fast-acting, not eating right after a dose of this insulin may lead to low blood sugar (hypoglycemia). Giving insulin regular into a vein should only be done by a health care professional. Very low blood sugar may result. Do not use insulin regular in an insulin pump. This product may be mixed only with certain other insulin products such as NPH insulin. Always draw the insulin regular into the syringe first, then follow with the longer-acting insulin. Never inject a mixture of different insulins into a vein. Consult your health care professional about which products may be mixed, the proper method for mixing insulin, and the proper way to inject mixtures of insulin. Do not change brands or types of insulin without directions on how to do so from your doctor. Learn how to store and discard medical supplies safely. The dosage is based on your medical condition and response to treatment. Measure each dose very carefully because even small changes in the amount of insulin may have a large effect on your blood sugar levels. Check your urine/blood sugar level as directed by your doctor. Keep track of your results and share them with your doctor. This is very important in order to determine the correct insulin dose. Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

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Tell your doctor if you are taking any medicines, including those bought over-the-counter and herbal medicines, before you start treatment with Diclofenac Sodium EC. Similarly, check with your doctor or pharmacist before you take any new medicines while you are taking Diclofenac Sodium EC. Diclofenac Sodium EC may increase the blood levels of the following medicines: - lithium - digoxin - methotrexate. People taking Diclofenac Sodium EC with any of the above should be closely monitored by their doctor. There may be an increased risk of bleeding if Diclofenac Sodium EC is taken with blood-thinning or anti-clotting medicines (anticoagulants) such as warfarin. People taking Diclofenac Sodium EC with an anticoagulant should be closely monitored by their doctor. There may be an increased risk of side effects such as stomach irritation if Diclofenac Sodium EC is taken with corticosteroids such as prednisolone. Diclofenac Sodium EC should not be taken with any other NSAID, eg ibuprofen, as this increases the risk of side effects, particularly on the gut. Ciclosporin may increase the blood level of Diclofenac Sodium EC, and your doctor may prescribe a lower than normal dose of diclofenac if you are taking ciclosporin. There may be an increased risk of side effects on the kidneys if Diclofenac Sodium EC is taken with any of the following medicines: - ciclosporin - ACE inhibitors, eg enalapril - diuretics, eg frusemide (furosemide). Diclofenac Sodium EC may reduce the blood pressure lowering effects of diuretics such as frusemide (furosemide). There may potentially be an increased risk of seizures if Diclofenac Sodium EC is taken together with quinolone antibiotics such as ciprofloxacin. Sodium hydroxide, as needed for pH adjustment to 8.1 to 8.3Side effects of moderate or severe intensity included insomnia (up to 7%), depression (up to 5%), anxiety (up to 4%), abnormal dreams (up to 3%), and nervousness (up to 2%).[Ref]changes in vision such as loss of vision, blurred vision, eyes being more sensitive to light, or trouble telling the difference between blue and green objects or objects having a blue color tinge to them

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Rashes were usually mild-to-moderate maculopapular skin eruptions. The median time to onset of rash in adults was 11 days. In most patients, the rash resolved within 1 month despite continued use of the drug. Treatment was discontinued in 1.7% of patients due to rash.

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Possible food and drug interactions when taking Diclofenac PRECAUTIONS: Before taking zonisamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease (such as kidney stones), lung/breathing problems, long-term diarrhea, metabolic imbalance (metabolic acidosis), a special diet (ketogenic diet), mental/mood problems (such as depression, psychosis). This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may decrease your ability to sweat, making you more likely to get heat stroke. Avoid activities that may cause you to overheat (such as doing strenuous work/exercise in hot weather, using hot tubs). When the weather is hot, drink plenty of fluids and dress lightly. If you become overheated, promptly seek cooler shelter and s exercising. Get medical help right away if you develop a fever, mental/mood changes, headache, or dizziness. Children may be more sensitive to the side effects of the drug, especially decreased sweating, heat stroke, or metabolic imbalance. During pregnancy, this medication should be used only when clearly needed. It may harm an unborn baby. However, since untreated seizures are a serious condition that can harm both a pregnant woman and her unborn baby, do not s taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately talk to your doctor about the benefits and risks of using this medication during pregnancy. This medication passes into breast milk. Consult your doctor before breast-feeding.

The tip cap and rubber plunger of the prefilled syringe are not made with natural rubber latex.

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